Mennonite Central Committee workers arrived in the West Bank in 1950 to assist Palestinian refugees displaced during the 1948 Arab-Israeli War. Since then Mennonites have been involved in a variety of ministries in Palestine and Israel, from a hospital in Nazareth to scholarly research in Jerusalem to an English Language program in Gaza City. Authors in this issue of Anabaptist Witness reflect on 75 years of Mennonite witness in the region, in addition to topics such as challenges raised for Anabaptists by Palestinian liberation theology; the 2017 Mennonite Church USA resolution “Seeking Peace in Israel and Palestine”; and recent efforts to organize Mennonites in the US to call for a ceasefire in Gaza and an end to the Israeli occupation of Palestinian territory. The issue includes essays, sermons, poetry, and images.